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Our patients’ stories: fixing Brody’s omphalocele
By Maureen Simoncini Brody When I was 18 weeks pregnant my husband, Kenny, and I went in for a routine ultrasound. We were excited to find out if I was carrying a boy or a girl, but we found out much more than that. The ultrasound revealed that I was having a boy, but he would be born with a serious medical condition called an omphalocele. (It’s a birth defect where the baby’s intestine or other organs stick out of the belly button. In many cases only a thin layer of tissue covers the intestines.) Once it was established that our baby had an omphalocele, we were transferred to a doctor at our local hospita...
Source: Thrive, Children's Hospital Boston - March 22, 2013 Category: Pediatrics Authors: Guest Blogger Tags: All posts Diseases & conditions Our patients’ stories omphalocele our patients' stories surgery Terry Buchmiller Source Type: news

Stem cells and birth defects: Could gastroschisis be treated in utero?
Although Gianna was treated surgically, Dario Fauza, MD, hopes to someday use stem cells from the amniotic fluid, multiplied and returned to the womb, to naturally heal gastroschisis and other birth defects. (Courtesy Danielle DeCarlo) Six-year-old Gianna DiCarlo is an active dancer and gymnast. Though she’s a healthy eater now, Gianna’s stomach bears a long scar, a remnant of three surgeries she underwent as an infant. She was born with gastroschisis, a striking birth defect in which the abdominal wall doesn’t seal fully during fetal development. As a result, her intestines developed outside her body. Sh...
Source: Thrive, Children's Hospital Boston - July 13, 2016 Category: Pediatrics Authors: Nancy Fliesler Tags: Our Patients’ Stories Research and Innovation gastroschisis Source Type: news

LITFL Search
The problem with providing education in the hospital environment is the persistent and unwarranted use of Internet Explorer which acts like a cubist Picasso converter to contort the website into a random series of incoherent text boxes Review of the old site highlighted a few functionality issues. One of the most frustrating elements of moving to a scalable mobile responsive design was the dropdown menus. We had far too much information crammed into an unpredictable space which was only intermittently visible…so they have been discarded with the new build. We have decided to run with ‘single menu tabs’ li...
Source: Life in the Fast Lane - November 11, 2013 Category: Emergency Medicine Doctors Authors: Mike Cadogan Tags: Blog News Featured Google Tips and Tricks blogging LITFL LITFL search Source Type: blogs

Facebook Graph Search in Medicine
Everyone has heard about the new Graph Search function on Facebook. It says “Want to start a book club or find a gym buddy? Connect with friends who like the same activities—and meet new people, too.” It will let Facebook users do searches by choosing different parameters (e.g. who goes to the same gym as me and is single). Well, many bloggers are optimistic about this launch and think it will be used in medicine too. I don’t think so and everyone should hope I’ll be right. It’s fun to identify friends in my community who I share the same multiple interests with (e.g. sci-fi and reading book...
Source: ScienceRoll - January 26, 2013 Category: Geneticists and Genetics Commentators Authors: Dr. Bertalan Meskó Tags: Facebook Health 2.0 Medical Search Medicine Medicine 2.0 Video Web 2.0 Source Type: blogs

Coexisting Gastrointestinal and Hepatobiliary Tract Anomalies in Omphalocele and Gastroschisis: A Twenty-Year Experience in a Single Tertiary Medical Center
This study aimed to investigate the demographic characteristics, coexisting congenital gastrointestinal and hepatobiliary tract anomalies, hospital course, and outcomes of patients with gastroschisis and omphalocele.
Source: Pediatrics and Neonatology - May 18, 2022 Category: Perinatology & Neonatology Authors: Chen-Chen Wen, Tien-Chueh Kuo, Hung-Chang Lee, Chun-Yan Yeung, Wai-Tao Chan, Chuen-Bin Jiang, Jin-Cherng Sheu, Nien-Lu Wang, Chyong-Hsin Hsu, Shu-Chao Weng, Yufeng Jane Tseng Tags: Original Article Source Type: research

Relationship between volume and outcome for gastroschisis: a systematic review protocol
DiscussionGiven the lack of a comprehensive summary of findings on the relationship between hospital or surgeon volume and outcomes for gastroschisis, this systematic review will put things right. Results can be used to inform decision makers or clinicians and to adapt medical care.Systematic review registrationOpen Science Framework (DOI:https://doi.org/10.17605/OSF.IO/EX34M;https://doi.org/10.17605/OSF.IO/HGPZ2)
Source: Systematic Reviews - September 1, 2020 Category: International Medicine & Public Health Source Type: research

Prevalence and Spatial Distribution of Gastroschisis in an Industrial Watershed
We examined gastroschisis incidence, risk factors, and spatial association in a geographic region with known environmental pollution and hazardous waste sites. An observational study of fetal and neonatal gastroschisis diagnosed from 1/1/2006 to 12/31/2020 was conducted in a southern West Virginia (WV) tertiary care hospital. Emerging hot spot analysis and Ripley's K-Function examined the spatial relationship between gastroschisis cases and Environmental Protection Agency (EPA) Federal Registry Sites (FRS). A total of 63 gastroschisis cases provided a prevalence rate of 14.6 per 10000 live births. Gastroschisis was associa...
Source: The American Surgeon - July 26, 2023 Category: Surgery Authors: Jacob Minor Amy Wells Krysta Orminski Stephanie N Thompson Frank Annie Lindsey Robinson Byron C Calhoun Ramanathapura N Haricharan Source Type: research

Hospital Variation in Surgical Technique for Repair of Uncomplicated Gastroschisis
Am Surg. 2022 May 12:31348221101511. doi: 10.1177/00031348221101511. Online ahead of print.ABSTRACTPractices in surgical repair of uncomplicated gastroschisis are varied. Data regarding hospital volume, surgical technique, clinical outcomes, and costs remain limited. Neonatal patients with uncomplicated gastroschisis were identified using the 2015-2019 National Readmissions Database. Hospital volume tertiles were determined, and sutureless or fascial repair techniques were enumerated. High volume centers (HVC) comprised the top tertile. Hospital-level variability in surgical technique was determined. Adjusted multivariable...
Source: The American Surgeon - May 13, 2022 Category: Surgery Authors: Catherine G Williamson Ayesha Ng Shannon Richardson Erica Li Peyman Benharash Daniel A DeUgarte Justin P Wagner Source Type: research

Prevalence and risk factors for gastroschisis in a public hospital from west México
Abstract Mexico is recognized as a country with a high prevalence of gastroschisis, although the cause of this remains unclear. We define the prevalence and potential risk factors for gastroschisis in a public hospital from West México. A case‐control study was conducted among 270 newborns, including 90 patients with nonsyndromic gastroschisis (cases) and 180 infants without birth defects (controls), born all during the period 2009 to 2013 at the Hospital Civil de Guadalajara “Dr. Juan I. Menchaca” (Guadalajara, Mexico), from out of a total of 51,145 livebirths. Potential maternal risk factors for gastroschisis were...
Source: Congenital Anomalies - August 1, 2014 Category: Genetics & Stem Cells Authors: Mireya Robledo‐Aceves, Lucina Bobadilla‐Morales, Estrella Lizbeth Mellín‐Sánchez, Alfredo Corona‐Rivera, J. Jesús Pérez‐Molina, Juan José Cárdenas‐Ruiz Velasco, Jorge Román Corona‐Rivera Tags: Original Article Source Type: research

Breastfeeding success in infants with giant omphalocele.
Abstract Infants born with a giant omphalocele often require multiple surgeries requiring a lengthy hospital stay. These vulnerable infants may experience a long period of being NPO (nothing by mouth), followed by slowly advancing to enteral feeds. Human milk is the ideal method of nutrition for all infants and should be used to initiate enteral feeds in infants recovering from omphalocele closure surgeries. Human milk provides immunological, nutritional, and developmental benefits for high-risk infants and may play a critical role in preventing associated morbidities often associated with infants born with giant ...
Source: Advances in Neonatal Care - December 1, 2012 Category: Nursing Authors: Spatz DL, Schmidt KJ Tags: Adv Neonatal Care Source Type: research

Associated congenital anomalies in infants with isolated gastroschisis: A single‐institutional experience
The aim of our study was to determine the frequency and type of associated congenital anomalies in patients with isolated gastroschisis born at the Dr. Juan I. Menchaca Civil Hospital of Guadalajara (Guadalajara, México), and to explore its possible association with the included outcome variables. One hundred‐eight cases with isolated gastroschisis were reviewed from 2009 to 2014. The occurrence of intestinal and extraintestinal associated anomalies (either secondary or primary) was prospectively assessed. The type of gastroschisis, length of hospital stay (LOS), and in‐hospital mortality were outcome variables for st...
Source: American Journal of Medical Genetics Part A - October 1, 2015 Category: Genetics & Stem Cells Authors: Jorge Román Corona‐Rivera, Rafael Nieto‐García, Eloy López‐Marure, Juan José Cárdenas‐Ruiz Velasco, Lucina Bobadilla‐Morales, Estrella Lizbeth Mellín‐Sánchez, Rafael L. Aguirre‐Guillén, René O. Pérez‐Ramírez, Eugenio Zapata‐Al Tags: Research Article Source Type: research

Infant, maternal, and geographic factors influencing gastroschisis related mortality in Zimbabwe
This study describes the burden of gastroschisis at the major pediatric hospital in Zimbabwe with the goal of identifying modifiable factors influencing gastroschisis-related infant mortality.
Source: Surgery - June 10, 2015 Category: Surgery Authors: Jordan. C. Apfeld, Sherry M. Wren, Nyasha Macheka, Bothwell A. Mbuwayesango, Matias Bruzoni, Karl. G. Sylvester, Zachary. J. Kastenberg Tags: Original Communication Source Type: research

Maternal factors associated with the occurrence of gastroschisis
ABSTRACT We sought to identify age group specific maternal risk factors for gastroschisis. Maternal characteristics and prenatal factors were compared for 1,279 live born infants with gastroschisis and 3,069,678 without. Data were obtained using the California database containing linked hospital discharge, birth certificate and death records from 1 year prior to the birth to 1 year after the birth. Backwards‐stepwise logistic regression models were used with maternal factors where initial inclusion was determined by a threshold of p < 0.10 on initial crude analyses. Due to the strong association of gastroschisis w...
Source: American Journal of Medical Genetics Part A - April 25, 2015 Category: Genetics & Stem Cells Authors: Rebecca J. Baer, Christina D. Chambers, Kenneth Lyons Jones, Stephen B. Shew, Tippi C. MacKenzie, Gary M. Shaw, Laura L. Jelliffe‐Pawlowski Tags: Research Article Source Type: research

Gastroschisis: A Review of Management and Outcomes
We performed an evidence-based review of the obstetrical management of gastroschisis. Gastroschisis is an abdominal wall defect, which has increased in frequency in recent decades. There is variation of prevalence by ethnicity and several known maternal risk factors. Herniated intestinal loops lacking a covering membrane can be identified with prenatal ultrasonography, and maternal serum α-fetoprotein level is commonly elevated. Because of the increased risk for growth restriction, amniotic fluid abnormalities, and fetal demise, antenatal testing is generally recommended. While many studies have aimed to identify antenata...
Source: Obstetrical and Gynecological Survey - September 1, 2016 Category: OBGYN Tags: CME Articles Source Type: research